Synuclein and the Coelacanth
  • Author : James M. Gruschus
  • Release Date : 01 March 2021
  • Publisher : Academic Press
  • Genre : Medical
  • Pages : 316
  • ISBN 13 : 9780323857079

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Book excerpt: Most neurodegenerative diseases have animal parallels such as Alzheimer's in chimpanzees, multiple sclerosis in macaques, Lou Gehrig's disease in dogs, but nothing like Parkinson's has ever been seen in any species but humans. Synuclein and the Coelacanth: The Molecular and Evolutionary Origins of Parkinson's Disease delves into the causes of Parkinson's disease and how the evolution of the human brain has left us uniquely vulnerable. Genetic risk factors, environmental toxins, and neuroanatomy are woven together in a multidisciplinary discussion that ranges from subatomic physics to socioeconomics. Connections between neurodegenerative disease, neural pathways, and innate immunity are explored. Finally, the author discusses new therapeutic agents are being developed that hope to go beyond just treating the symptoms of Parkinson's and actually halt the disease. Proposes a new hypothesis on the origins of Parkinson's disease Examines genetic risk factors, environmental toxins, and neuroanatomy of PD Highlights new therapeutic treatment options in development for patients

Synuclein and the Coelacanth

Synuclein and the Coelacanth

Author : James M. Gruschus
Publisher : Academic Press
Genre : Medical
Get Book

Most neurodegenerative diseases have animal parallels such as Alzheimer's in chimpanzees, multiple sclerosis in macaques, Lou Gehrig's disease in dogs, but nothing like Parkinson's has ever been seen in any species but humans. Synuclein and the Coelacanth: The Molecular and Evolutionary Origins of Parkinson's Disease delves into the causes of ...

Synuclein and the Coelacanth

Synuclein and the Coelacanth

Author : James M. Gruschus
Publisher : Academic Press
Genre : Medical
Get Book

Most neurodegenerative diseases have animal parallels such as Alzheimer’s in chimpanzees, multiple sclerosis in macaques, Lou Gehrig’s disease in dogs, but nothing like Parkinson’s has ever been seen in any species but humans. Synuclein and the Coelacanth: The Molecular and Evolutionary Origins of Parkinson's Disease delves into ...

Evolution of the Protein Synthesis Machinery and Its Regulation

Evolution of the Protein Synthesis Machinery and Its Regulation

Author : Greco Hernández,Rosemary Jagus
Publisher : Springer
Genre : Science
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The “omics” era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective. Written by leading experts in molecular biology, this text looks into the ...

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The Networking of Chaperones by Co chaperones

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Publisher : Springer
Genre : Medical
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Co-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is a dynamic balance between the integrated processes of protein folding, degradation and translocation. The Networking of Chaperones by Co-chaperones describes how the function of the major molecular chaperones is regulated by a cohort of diverse non-client ...

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Publisher : Springer
Genre : Medical
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Publisher : Springer
Genre : Medical
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This 5000-page masterwork is literally the last word on the topic and will be an essential resource for many. Unique in its breadth and detail, this encyclopedia offers a comprehensive and highly readable guide to a complex and fast-expanding field. The five-volume reference work gathers more than 10,000 entries, including in-depth ...

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Publisher : Unknown
Genre : Science
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Publisher : Oxford University Press, USA
Genre : Science
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Publisher : MIT Press
Genre : Psychology
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A leading neurobiologist explores the fundamental function of dendritic spines in neural circuits by analyzing different aspects of their biology, including structure, development, motility, and plasticity. Most neurons in the brain are covered by dendritic spines, small protrusions that arise from dendrites, covering them like leaves on a tree. But ...

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Author : Anonim
Publisher : Elsevier
Genre : Science
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This volume of Advances in Protein Chemistry provides a broad, yet deep look at the cellular components that assist protein folding in the cell. This area of research is relatively new--10 years ago these components were barely recognized, so this book is a particularly timely compilation of current information. Topics ...

Genetics  Neurology  Behavior  and Diet in Dementia

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Author : Colin R. Martin,Victor R Preedy
Publisher : Academic Press
Genre : Medical
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Genetics, Neurology, Behavior, and Diet in Dementia: The Neuroscience of Dementia, Volume 2 consolidates different fields of dementia research into a single book, covering a range of subjects, including Alzheimer’s disease, Lewy body dementia, mixed dementia, vascular dementia, physical activity, risk factors, mortality, biomarkers, SPECT, CT, MRI, questionnaires, nutrition, sleep, ...

Genetics  Neurology  Behavior  and Diet in Parkinson s Disease

Genetics Neurology Behavior and Diet in Parkinson s Disease

Author : Colin R. Martin,Victor R Preedy
Publisher : Academic Press
Genre : Medical
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Genetics, Neurology, Behavior, and Diet in Parkinson's Disease: The Neuroscience of Parkinson’s Disease, Volume 2 provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, ...

The Zebrafish in Biomedical Research

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Author : Samuel Cartner,Judith S. Eisen,Susan F. Farmer,Karen J. Guillemin,Michael L. Kent,George E. Sanders
Publisher : Academic Press
Genre : Science
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The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ...

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Author : Anton Ficai,Alexandru Mihai Grumezescu
Publisher : Elsevier
Genre : Medical
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Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As ...