Molecular Diagnostics and Treatment of Pancreatic Cancer
  • Author : Asfar Azmi
  • Release Date : 14 April 2014
  • Publisher : Elsevier
  • Genre : Medical
  • Pages : 458
  • ISBN 13 : 9780124079465

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Book excerpt: Molecular Diagnostics and Treatment of Pancreatic Cancer describes the different emerging applications of systems biology and how it is shaping modern pancreatic cancer research. This book begins by introducing the current state of the art knowledge, trends in diagnostics, progress in disease model systems as well as new treatment and palliative care strategies in pancreatic cancer. Specific sections are dedicated to enlighten the readers to newer discoveries that have emerged from gene expression profiling, proteomics, metabolomics and systems level analyses of pancreatic cancer datasets. First of a kind and novel network strategies to understand oncogenic Kras signaling in pancreatic tumors are presented. The attempts to computationally model and prioritize microRNAs that cause pancreatic cancer resistance are also highlighted. Addressing this important area, Molecular Diagnostics and Treatment of Pancreatic Cancer provides insights into important network evaluation methodologies related to pancreatic cancer related microRNAs targetome. There are dedicated chapters on critical aspects of the evolving yet controversial field of pancreatic cancer stems cells. The work concludes by discussing the applications of network sciences in pancreatic cancer drug discovery and clinical trial design. Encompasses discussion of innovative tools including expression signatures in cell lines, 3D models, animal xenograft models, primary models and patient derived samples, aiding subversion of traditional biology paradigms, and enhancing comprehension across conventional length and temporal scales Coverage includes novel applications in targeted drugs, polypharmacology, network pharmacology and other related drug development arenas – helping researchers in pancreatic cancer drug discovery Summarizes many relevant computational and clinical references from fast-evolving literature Comprehensive glossary helps newer readers understand technical terms and specialized nomenclature

Molecular Diagnostics and Treatment of Pancreatic Cancer

Molecular Diagnostics and Treatment of Pancreatic Cancer

Author : Asfar Azmi
Publisher : Elsevier
Genre : Medical
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Molecular Diagnostics and Treatment of Pancreatic Cancer describes the different emerging applications of systems biology and how it is shaping modern pancreatic cancer research. This book begins by introducing the current state of the art knowledge, trends in diagnostics, progress in disease model systems as well as new treatment and ...

Molecular Diagnostics and Treatment of Pancreatic Cancer

Molecular Diagnostics and Treatment of Pancreatic Cancer

Author : Asfar Azmi
Publisher : Academic Press
Genre : Medical
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Molecular Diagnostics and Treatment of Pancreatic Cancer describes the different emerging applications of systems biology and how it is shaping modern pancreatic cancer research. This book begins by introducing the current state of the art knowledge, trends in diagnostics, progress in disease model systems as well as new treatment and ...

Theranostic Approach for Pancreatic Cancer

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Publisher : Academic Press
Genre : Science
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Theranostic Approach for Pancreatic Cancer modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property through introducing new strategies and drugs for tackling the disease. It brings information about ongoing research as well as clinical data about pancreatic cancer ...

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Publisher : Springer
Genre : Medical
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Genre : Medical
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Publisher : Lippincott Williams & Wilkins
Genre : Medical
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The role of molecular genetics in the treatment of malignancy continues to grow at an astonishing rate. Today’s subspecialized multidisciplinary approach to oncology has incorporated advances in targeted molecular therapy, prognosis, risk assessment, and prevention—all based at least in part on molecular diagnostics and imaging. Inside this cutting-edge ...

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Publisher : Springer Science & Business Media
Genre : Medical
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Publisher : Springer Science & Business Media
Genre : Medical
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Publisher : Academic Press
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Publisher : Academic Press
Genre : Business & Economics
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Publisher : Springer Science & Business Media
Genre : Medical
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Publisher : Springer Nature
Genre : Medical
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This book covers the discovery of molecular biomarkers, the development of laboratory testing techniques and their clinical applications, focusing on basic research to clinical practice. It introduces new and crucial knowledge and ethics of clinical molecular diagnosis. This book emphasizes the applications of clinical molecular diagnostic test on health management, ...

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Publisher : Academic Press
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