Mitochondria in Obesity and Type 2 Diabetes
  • Author : Beatrice Morio
  • Release Date : 13 April 2019
  • Publisher : Academic Press
  • Genre : Science
  • Pages : 459
  • ISBN 13 : 9780128118597

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Book excerpt: Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key concepts on topics such as the role of mitochondria in adipose tissue, cancer, cardiovascular comorbidities, skeletal muscle, the liver, kidney, and more. This book is a must-have reference for students and educational teams in biology, physiology and medicine, and researchers. Synthesizes actual knowledge on mitochondrial function Provides an integrated vision of each tissue in the etiology of obesity and type 2 diabetes Identifies the interactive networks that involve alteration in mitochondrial mass and function in disease progression Highlights the role played by mitochondria in the prevention and treatment of obesity and type 2 diabetes

Mitochondria in Obesity and Type 2 Diabetes

Mitochondria in Obesity and Type 2 Diabetes

Author : Beatrice Morio,Luc Penicaud,Michel Rigoulet
Publisher : Academic Press
Genre : Science
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Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key ...

Mitochondria in Obesity and Type 2 Diabetes

Mitochondria in Obesity and Type 2 Diabetes

Author : Beatrice Morio,Luc Penicaud,Michel Rigoulet
Publisher : Academic Press
Genre : Science
Get Book

Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key ...

Targeting Mitochondrial Pathways in Obesity and Type 2 Diabetes

Targeting Mitochondrial Pathways in Obesity and Type 2 Diabetes

Author : Jessica Erin Sacks
Publisher : Unknown
Genre : Insulin resistance
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Obesity is one of the largest medical epidemics our society faces today. There are over forty obesity-associated diseases that affect nearly every organ system in the body, including Type 2 Diabetes (T2D) and Non-Alcoholic Fatty Liver Disease (NAFLD). Insulin resistance is one of the hallmark characteristics underlying metabolic diseases, and ...

Mitochondrial Function

Mitochondrial Function

Author : Anonim
Publisher : Academic Press
Genre : Science
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This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. Methods to assess mitochondrial function is of great interest to neuroscientists studying chronic forms of neurodegeneration, including Parkinson's, Alzheimer's, ALS, Huntington's and other triplet repeat diseases, but ...

Mitochondria in Pathogenesis

Mitochondria in Pathogenesis

Author : John J. Lemasters,Anna-Liisa Nieminen
Publisher : Springer Science & Business Media
Genre : Science
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Mitochondria are organelles in each cell outside the nucleus and are the energy source of all cells. As such, they are crucial to the healthy functioning of cells. Recent research has shown that mitochondrial dysfunction underlies a broad spectrum of disease, from maternally inherited genetic disorders to metabolism defects, aging, ...

Advances in Mitochondrial Medicine

Advances in Mitochondrial Medicine

Author : Roberto Scatena,Patrizia Bottoni,Bruno Giardina
Publisher : Springer Science & Business Media
Genre : Medical
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Mitochondria are far more than the “powerhouse” of the cell as they have classically been described. In fact, mitochondria biological activities have progressively expanded to include not only various bioenergetic processes but also important biosynthetic pathways, calcium homeostasis and thermogenesis, cell death by apoptosis, several different signal transduction pathways mainly ...

Organelle Contact Sites

Organelle Contact Sites

Author : Mitsuo Tagaya,Thomas Simmen
Publisher : Springer
Genre : Science
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This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS). A total of 16 chapters explain their organization and role and unveil the significance of MCS for various diseases. MCS, the intracellular structures where organellar membranes come in close contact with one another, ...

Mitochondrial Dynamics in Cardiovascular Medicine

Mitochondrial Dynamics in Cardiovascular Medicine

Author : Gaetano Santulli
Publisher : Springer
Genre : Science
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This text covers the basic principles of mitochondrial dynamics in cardiovascular medicine, with particular emphasis on their functional roles in physiology and disease. The book will include articles pertaining to mitochondrial fitness on a global basis, providing therefore an update on the progress made in several aspects in the field. ...

Oxidative Stress and Inflammatory Mechanisms in Obesity  Diabetes  and the Metabolic Syndrome

Oxidative Stress and Inflammatory Mechanisms in Obesity Diabetes and the Metabolic Syndrome

Author : Helmut Sies
Publisher : CRC Press
Genre : Medical
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Characterized by obesity, insulin resistance, dyslipidemia, and hypertension, metabolic syndrome is associated with the risks of type 2 diabetes mellitus and cardiovascular disease. Obesity, which increases the incidence of atherosclerotic cardiovascular disease and subsequently leads to increased stress and inflammation, appears to play a central role in the progression of the ...

Adiposity

Adiposity

Author : Jan Gordeladze
Publisher : BoD – Books on Demand
Genre : Medical
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This book is the second in a series of two, featuring the Adiposity - Omics and Molecular Understanding, serving as an introduction to modern views on how the adipocytes are reciprocally interacting with organ systems in order to explain the biology of the body's fat cells and how they are ...

Pathophysiology of Obesity Induced Health Complications

Pathophysiology of Obesity Induced Health Complications

Author : Paramjit S. Tappia,Bram Ramjiawan,Naranjan S. Dhalla
Publisher : Springer Nature
Genre : Medical
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​According to the World Health Organization, the epidemic of global obesity has nearly tripled since 1975. In 2016, more than 1.9 billion adults were overweight, over 650 million of which were obese. Being overweight and obese has been linked to a number of non-communicable, chronic diseases. Pathophysiology of Obesity-Induced Health Complications is a compilation ...

Muscle Metabolism

Muscle Metabolism

Author : Juleen R Zierath,Harriet Wallberg-Henrikss
Publisher : CRC Press
Genre : Medical
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Diabetes research on models comprising intact animal tissues, cell cultures and isolated pancreatic islets is essential for understanding the pathogenesis of the disease as well as the mechanisms responsible for the chronic complications associated with it. Enormous advances in the understanding of the development of diabetes and its prevention hav...

Muscle Biophysics

Muscle Biophysics

Author : Rassier Dilson J.E
Publisher : Springer Science & Business Media
Genre : Science
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Muscle contraction has been the focus of scientific investigation for more than two centuries, and major discoveries have changed the field over the years. Early in the twentieth century, Fenn (1924, 1923) showed that the total energy liberated during a contraction (heat + work) was increased when the muscle was allowed to shorten ...