Chromatin Readers in Health and Disease
  • Author : Olivier Binda
  • Release Date : 15 December 2021
  • Publisher : Academic Press
  • Genre : Medical
  • Pages : 416
  • ISBN 13 : 0128233761

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Book excerpt: Chromatin Readers in Health and Disease, Volume 32, a new release in the Translational Epigenetics series, gathers and makes actionable our current understanding of how chromatin readers regulate access to genetic information, and how their aberrant regulation can contribute to human pathologies. Chromatin readers discussed include 14-3-3 Dinshaw, ADD, Ankyrin, BAH, BET, BIR, BRCT, bromodomains and Kac readers, chromodomains and chromobarrel readers, citrullination readers, macrodomains and poly-ADP-ribose readers, MBT, PHD and double PHD, PWWP, SUMO (H4K12) readers, Tudor and TTD, UDR and ubiquitin, WD40, YEATS (crotonyl reader)?, MBD, SRA, and Methyl-RNA readers. In the book, more than a dozen leaders in the field examine a range of protein readers, their relationship to human disease, and the early therapeutics that act as chromatin signaling factors to treat cancers and Huntington's disease, among other disorders. Enables researchers and clinicians to understand chromatin signaling mechanisms that regulate gene expression through chromatin readers Highlights the role of chromatin readers in a variety of human pathologies, as well as early therapeutics that act on chromatin signaling Includes chapter contributions from international leaders in the field

Chromatin Readers in Health and Disease

Chromatin Readers in Health and Disease

Author : Olivier Binda
Publisher : Academic Press
Genre : Medical
Get Book

Chromatin Readers in Health and Disease, Volume 32, a new release in the Translational Epigenetics series, gathers and makes actionable our current understanding of how chromatin readers regulate access to genetic information, and how their aberrant regulation can contribute to human pathologies. Chromatin readers discussed include 14-3-3 Dinshaw, ADD, Ankyrin, ...

Environmental Epigenomics in Health and Disease

Environmental Epigenomics in Health and Disease

Author : Randy L Jirtle,Frederick L. Tyson
Publisher : Springer Science & Business Media
Genre : Medical
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There are now compelling human epidemiological and animal experimental data that indicate the risk of developing adult-onset complex diseases and neurological disorders are influenced by persistent epigenetic adaptations in response to prenatal and early postnatal exposures to environmental factors. Epigenetics refers to heritable changes in gene function that occur without ...

Transcriptional Gene Regulation in Health and Disease

Transcriptional Gene Regulation in Health and Disease

Author : Anonim
Publisher : Academic Press
Genre : Science
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Transcriptional Gene Regulation in Health and Disease, Volume 335, the latest release in the International Review of Cell and Molecular Biology reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics ...

Chromatin Signaling and Diseases

Chromatin Signaling and Diseases

Author : Olivier Binda,Martin Ernesto Fernandez-Zapico
Publisher : Academic Press
Genre : Science
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Chromatin Signaling and Diseases covers the molecular mechanisms that regulate gene expression, which govern everything from embryonic development, growth, and human pathologies associated with aging, such as cancer. This book helps researchers learn about or keep up with the quickly expanding field of chromatin signaling. After reading this book, clinicians ...

Human Epigenomics

Human Epigenomics

Author : Carsten Carlberg,Ferdinand Molnár
Publisher : Springer
Genre : Medical
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The term epigenetics describes regulatory and information storing mechanisms of specific genes that do not involve any change of their DNA sequence. Epigenetics is closely related to the extensively folded state, in which the genome is packaged, known as chromatin. New genomic tools nowadays allow the genome-wide assessment of, for ...

Epigenomics in Health and Disease

Epigenomics in Health and Disease

Author : Mario Fraga,Agustin Fernandez Fernandez
Publisher : Academic Press
Genre : Science
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Epigenomics in Health and Disease discusses the next generation sequencing technologies shaping our current knowledge with regards to the role of epigenetics in normal development, aging, and disease. It includes the consequences for diagnostics, prognostics, and disease-based therapies made possible by the study of the complete set of epigenetic modifications ...

Human Epigenetics  How Science Works

Human Epigenetics How Science Works

Author : Carsten Carlberg,Ferdinand Molnár
Publisher : Springer Nature
Genre : Medical
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The view “It’s all in our genes and we cannot change it” developed in the past 150 years since Gregor Mendel’s experiments with flowering pea plants. However, there is a special form of genetics, referred to as epigenetics, which does not involve any change of our genes but regulates ...

Mechanisms of Gene Regulation

Mechanisms of Gene Regulation

Author : Carsten Carlberg,Ferdinand Molnár
Publisher : Springer
Genre : Medical
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This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of gene expression is a fundamental aspect of nearly all processes ...

Genome Plasticity in Health and Disease

Genome Plasticity in Health and Disease

Author : Anonim
Publisher : Academic Press
Genre : Medical
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Genome Plasticity in Health and Disease provides a fully up-to-date overview on genome plasticity and its role in human physiology and disease. Following an introduction to the field, a diverse range of chapters cover genomic and epigenomic analysis and the use of model organisms and genomic databases in studies. Specific ...

Systems Analysis of Chromatin Related Protein Complexes in Cancer

Systems Analysis of Chromatin Related Protein Complexes in Cancer

Author : Andrew Emili,Jack Greenblatt,Shoshana Wodak
Publisher : Springer Science & Business Media
Genre : Medical
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​​​​​​​​​​​​​​​​​​​​​​​ Epigenetic modifications underlie all aspects of human physiology, including stem cell renewal, formation of cell types and tissues. They also underlie environmental impacts on human health, including aging and diseases like cancer. Consequently, cracking the epigenetic "code" is considered a key challenge in biomedical research. Chromatin structure and function are ...

The Epigenome and Developmental Origins of Health and Disease

The Epigenome and Developmental Origins of Health and Disease

Author : Cheryl S Rosenfeld
Publisher : Academic Press
Genre : Science
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The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring. The book mines the existing literature from a variety ...

Toxicoepigenetics

Toxicoepigenetics

Author : Shaun D. McCullough,Dana Dolinoy
Publisher : Academic Press
Genre : Medical
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Toxicoepigenetics: Core Principles and Applications examines the core aspects of epigenetics, including chromatin biology, DNA methylation, and non-coding RNA, as well as fundamental techniques and considerations for studying each of these mechanisms of epigenetic regulation. Although its integration into the field of toxicology is in its infancy, epigenetics have taken ...

RNA Based Regulation in Human Health and Disease

RNA Based Regulation in Human Health and Disease

Author : Anonim
Publisher : Academic Press
Genre : Medical
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RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and ...

Pocket Companion to Robbins   Cotran Pathologic Basis of Disease E Book

Pocket Companion to Robbins Cotran Pathologic Basis of Disease E Book

Author : Richard N Mitchell,Vinay Kumar,Nelson Fausto,Abul K. Abbas,Jon C. Aster
Publisher : Elsevier Health Sciences
Genre : Medical
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This pocket companion offers rapid, portable access to the most important pathology facts and concepts from Robbins and Cotran Pathologic Basis of Disease, 9th Edition. It distills the key concepts and principles of pathology into a condensed, at-a-glance format, making it the perfect reference for quick review anytime! Consult this ...